If you’re planning to visit Tijuana for dental treatment, getting there from San Diego is easier than you might think. With several transportation options available, you can choose what fits your comfort level, budget, and schedule. Below is a quick study of the main ways U.S. patients travel from San Diego to Tijuana dental clinics, plus the easiest option we provide at our dental clinic for patients flying into San Diego International Airport (SAN).
1. The San Diego Trolley (Blue Line)
The UC San Diego Blue Line runs directly from downtown San Diego to the San Ysidro Transit Center, which is located just a few steps from the U.S.–Mexico border. From there, you can walk through the PedEast pedestrian crossing into Tijuana and take a short taxi or Uber ride to your dental clinic.
Cost: Very affordable (local transit fare)
Pros: Frequent service, inexpensive, avoids driving
Cons: Requires walking across the border and arranging a ride on the Mexico side
This is one of the most popular options among frequent border crossers because it’s reliable and simple, though not ideal if you’re carrying heavy luggage.
2. Intercity Bus (Greyhound or FlixBus)
Both Greyhound and FlixBus offer low-cost service from San Diego to San Ysidro, the last U.S. stop before the border. Once you arrive, you can walk through PedEast and catch a local taxi or rideshare into Tijuana.
Cost: Around $8–$12 one way
Pros: Budget-friendly, comfortable, reserved seating
Cons: You’ll still need to walk across and arrange local transportation after crossing
This option is ideal for patients traveling from further north in California who prefer a straightforward, affordable connection to the border.
3. Rideshare or Taxi to the Border
If you prefer not to deal with bus schedules or parking, you can take an Uber, Lyft, or local taxi directly from your hotel or San Diego airport to the San Ysidro pedestrian crossing. Vehicles typically can’t cross into Mexico unless pre-authorized, so most travelers walk across and then request a new ride on the Tijuana side.
Cost: Moderate
Pros: Door-to-border service, convenient with luggage
Cons: Still requires crossing on foot and another ride in Tijuana
For first-time dental tourists, this is a safe and simple way to reach the border without worrying about navigation or parking.
4. CBX (Cross Border Xpress)
If you’re flying via Tijuana International Airport (TIJ), the Cross Border Xpress (CBX) bridge in Otay Mesa allows you to walk directly from the U.S. terminal to TIJ in just a few minutes. You’ll need to buy a CBX ticket, but it’s a modern, secure facility ideal for those arriving or departing by air.
Cost: CBX ticket fee + airfare
Pros: Fast, modern, avoids traffic, ideal for frequent flyers
Cons: Only for travelers flying through TIJ
Many U.S. travelers choose to book their return flight from TIJ and cross through CBX for maximum convenience.
5. Driving Your Own Car
Driving from San Diego into Tijuana gives you total flexibility. You can cross through San Ysidro (I-5) or Otay Mesa (SR-905), depending on where your clinic or hotel is located.
However, keep in mind that Mexico auto insurance is required — U.S. policies generally don’t apply once you cross the border. You’ll also need your passport and vehicle documents handy.
Cost: Fuel + temporary Mexican insurance
Pros: Full control of schedule, door-to-door travel
Cons: Must purchase insurance and plan for possible border wait times on return
If you plan to drive beyond the border zone, you may also need a temporary vehicle import permit.
The Easiest Option for Our Patients
At our dental clinic, we’ve simplified the process for our international patients. If you’re flying into San Diego International Airport (SAN), we offer direct airport pickup through our trusted international shuttle partner.
This door-to-clinic transportation is included with most of our treatment packages and covers:
Pickup from San Diego Airport
Transfer to your Tijuana hotel or clinic
Return transportation for your flight home
Patient + one companion included (additional companions may be added for a small fee)
Because we manage all the logistics, you won’t have to worry about crossing procedures, taxis, or luggage transfers. It’s by far the fastest and most stress-free way to get to your dental appointment in Tijuana.
Frequently Asked Questions
Is the trolley safe for first-time visitors?
Yes. The Blue Line is a clean, efficient option used daily by locals and travelers alike. Just remember to keep your passport accessible and follow signage to PedEast when you arrive at San Ysidro.
What’s the cheapest way to reach the border?
Greyhound or FlixBus typically offer the lowest fares and are great if you prefer a comfortable ride to the border without driving.
Can I drive my own car into Tijuana?
Yes, but you must purchase Mexican auto insurance before crossing. It’s quick and affordable online. Make sure to carry your U.S. driver’s license, registration, and proof of insurance.
What’s the typical wait time at the border?
The PedEast pedestrian crossing is open 24/7, and wait times usually range from 5 to 25 minutes, depending on the time of day and day of the week.
What’s the easiest way if I’m flying into San Diego?
Our Tijuana dental clinic’s airport shuttle is the best choice. We pick you up directly at the airport and handle your transportation to and from the clinic, all coordinated by our bilingual patient team.
No matter how you choose to travel, by trolley, bus, car, or CBX, reaching Tijuana for dental treatment is simple and affordable. However, for patients flying into San Diego, nothing compares to the comfort and convenience of our airport transfer service.
We take care of everything from the moment you land, ensuring your trip is safe, easy, and focused on what matters most: your new smile.
